Dec. 21, 2022 by Tim Murphy “A T cell (red) that’s been infected with HIV produces many copies of the virus (blue), as shown in this colorized transmission electron micrograph. HIV cure research continues to seek out ways to end this process once and for all.” Photo: NIAID “It seems as though a day did […]
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RIO’s Prof Sarah Fidler featured in a news piece celebrating 25 years of Imperial’s Faculty of Medicine and trailblazing HIV and AIDS research
1st Dec 2022 by Genevieve Timmins, Imperial College London The launch of Imperial’s Faculty of Medicine in 1997 coincided with a new era in HIV/AIDS treatment and research. Just prior to its creation came the groundbreaking revelation that combining three antiretroviral drugs could drastically improve the prognosis of people living with HIV. The subsequent rollout […]
The RIO Trial on World AIDS Day
1st December 2022 On this #WorldAIDSDay2022 we would like to thank all our participants for all their commitment and time for the #RIOTrial. The trial is still open for recruitment and midway to full enrollment. We look forward to sharing exciting updates from the study soon! […]
Long-awaited results of the eCLEAR study are out showing the impact of the bNAb ‘3BNC117’ in people with detectable viraemia
17 Oct 2022, Nature Medicine The eCLEAR study published their results in Nature Medicine in October. This study combined the use of 3BNC117, which is a broadly neutralising antibody (bNAb), with a potent latency reversing agent, romidepsin, to reduce the HIV reservoir in individuals starting antiretroviral treatment (ART) for the first time. The study was […]
Professor Sarah Fidler on BBC’s Newsnight programme
4th July 2022 Professor Sarah Fidler was interviewed on the BBC’s Newsnight programme last night together with the CEO of the Terrence Higgins Trust, Ian Green. It has been 40 years since the death of Terrence Higgins who was the first person in the UK to die of an AIDS-related illness. The interview covered important […]
Professors Sarah Fidler and John Frater on the bNAb vaccinal effect
Current Opinion in HIV and AIDS – May 2022 – Volume 17 – Issue 3 Our RIO Trial Chief Investigator Professor Sarah Fidler and Protocol Co-Chair Professor John Frater have contributed to a recent discussion piece on the vaccinal effect of the HIV bNAbs. Please read the article here, which was published in the May 2022 issue of the […]
Professor Sarah Fidler in the Shot & Chaser podcast
June 7, 2022 Listen to the latest Shot & Chaser podcast with our RIO Trial Chief Investigator, Professor Sarah Fidler, where she discusses the RIO Trial in the context of cure. Please follow this link to the podcast. […]
Nature publication: antibody therapy controls HIV for months in new clinical trial
Findings from a clinical trial led by Rockefeller University scientists as reported by journal Nature highlight anti-HIV antibodies as a novel treatment option; one that wouldn’t rely on vigilant daily dosing and could potentially reduce the body’s reservoir of HIV, which conventional antiretroviral drugs cannot do. Read the full article here […]
RIO Trial protocol published in the journal Trials
5 April 2022, 23, Article number: 263 We are pleased to report that the RIO Trial protocol has now been published in the peer-reviewed journal Trials. Please find the full manuscript here. […]
RIO trial update
We are delighted to note that we are currently recruiting in all 7 clinical sites across London and Brighton and will shortly be opening 3 new sites at St George’s Hospital in London, Western General Hospital in Edinburgh and North Manchester General Hospital. To date we have recruited and dosed 20 participants into the study. […]
